Synapsin® RG3 Nasal Spray
Rock Ridge Pharmacy – Promoting cognitive function and neurological health.
Customized Neurological Care • Prescription Required
Synapsin® (RG3) Nasal Spray Compounding
Advanced support for brain health, memory, and neuroinflammation, compounded at Rock Ridge Pharmacy in Glen Rock, NJ. Customized formulations prepared to meet patient and prescriber needs.
What Is Synapsin® RG3 Nasal Spray?
Synapsin® RG3 Nasal Spray is a breakthrough in cognitive support, formulated to enhance memory, focus, and overall brain health. Developed by pharmacist and functional medicine expert Jim LaValle, this patent-pending blend combines Ginsenoside Rg3 from Panax ginseng and nicotinamide riboside (Vitamin B3), with supporting ingredients that improve solubility and absorption.
At Rock Ridge Pharmacy, we further compound Synapsin® with methylcobalamin (Vitamin B12) to strengthen its neuroprotective and cognitive-enhancing benefits.
Delivered as a fast-absorbing nasal spray, Synapsin® provides targeted support for individuals experiencing brain fog, poor concentration, and cognitive decline.
Talk to your compounding pharmacist at Rock Ridge Pharmacy to learn how Synapsin® can support your personalized cognitive wellness plan.


Key Ingredients in Synapsin® RG3 Nasal Spray
Synapsin® RG3 Nasal Spray combines three clinically studied neuroprotective compounds. Together, they help reduce neuroinflammation, boost NAD+ metabolism, and support neuronal repair for sharper cognitive function and long-term brain health.
Ginsenoside Rg3
Extracted from Panax Ginseng, Rg3 reduces neuroinflammation and oxidative stress while promoting synaptic repair and mental clarity.
Nicotinamide Riboside (NR)
A Vitamin B3 derivative that restores NAD+ levels, boosting energy metabolism, focus, and resilience against cognitive decline.
Methylcobalamin (B12)
The active form of Vitamin B12 supports myelin repair, memory, and concentration while protecting against deficiency-related brain issues.
How Does Synapsin® RG3 Nasal Spray Work?
Synapsin® RG3 Nasal Spray is a pharmacist-formulated cognitive enhancement nasal spray that delivers neuroprotective ingredients directly to the brain through an advanced intranasal nootropic delivery system. Unlike oral supplements, Synapsin® bypasses digestion and the liver, ensuring rapid absorption via the nasal mucosa and delivering active compounds through the olfactory and trigeminal nerve pathways.
Why Synapsin® RG3 Works Faster

Who Can Benefit from RG3 (Synapsin®) Nasal Spray?
RG3 (Synapsin®) Nasal Spray supports individuals with cognitive and neurological challenges by reducing neuroinflammation, boosting brain energy, and promoting neuronal regeneration.
How to Use Synapsin® RG3 Nasal Spray
Synapsin® RG3 Nasal Spray delivers powerful neuroprotective ingredients— Ginsenoside Rg3, Nicotinamide Riboside (NR), and Methylcobalamin (B12)— directly to the brain via the nasal cavity for rapid absorption and fast cognitive support.
Dosing Instructions
- Follow Prescribed Directions: Use only as directed by your healthcare provider.
- Typical Use: 1–2 sprays daily, based on cognitive needs.
- Do Not Self-Adjust: Modify dosing only under professional supervision.
Application Tips
- How to Apply: Spray into each nostril as instructed for direct nasal absorption.
- Maximize Absorption: Blow your nose gently before use. Tilt your head back slightly and inhale while spraying.

Supplements to Support Synapsin® RG3 Therapy
Targeted supplements can help maximize Synapsin®’s cognitive benefits by supporting brain health, memory, and neuroimmune balance.

- OmegaPure 820™ Fish Oil – reduces neuroinflammation and protects brain cell membranes
- N-Acetyl-Cysteine (NAC) 600 mg – boosts glutathione and defends against oxidative stress
- Vitamin D₃ Complete 5000 IU – supports neuroimmune balance and overall brain health
- Probiotic – strengthens the gut-brain axis to support mood and cognition
These supplements complement Synapsin® therapy but do not replace prescription treatment. Ask our pharmacists about supportive supplementation for your personalized plan.
Storage & Safety Information for Synapsin® RG3 Nasal Spray
Storage Guidelines
Synapsin® RG3 Nasal Spray should be stored in the refrigerator to maintain potency and extend shelf life. Before each use, warm the bottle to room temperature by rolling it in your hands.
The spray can also be stored at 68°F–77°F (20°C–25°C) for up to 30 days. Keep it in a cool, dry place away from heat, sunlight, and moisture. Do not freeze, as this can damage the formula.
For safety, always keep Synapsin® RG3 out of reach of children and pets. Child-resistant packaging is available upon request.
Questions about storage, expiration, or handling? Call 201-444-4190 or email info@rockridgepharmacy.com.
Side Effects of Synapsin® RG3 Nasal Spray
Common side effects include mild nasal irritation or slight burning, occasional headaches or dizziness, and temporary flushing or light nausea. These effects are usually mild and short-lived. When to contact your provider: If you experience severe or persistent side effects, discontinue use and consult your healthcare provider promptly. Important reminder: Always follow your prescribed dosage and inform your provider of all medications and supplements to avoid potential interactions.
Disclaimer: This information is for educational purposes only and does not replace medical advice. Always consult your healthcare provider before starting or changing treatment with Synapsin® RG3 Nasal Spray.

Precautions Before Using Synapsin® RG3 Nasal Spray
Before starting Synapsin® RG3 Nasal Spray, inform your healthcare provider about your medical history, current medications, and supplements.
Key Precautions
- • Pregnancy & Breastfeeding: Consult your provider before use.
- • Caffeine Sensitivity: May enhance caffeine’s stimulant effects.
- • Hormone Therapy: Discuss use if on estrogen-based treatments.
- • Medication Interactions: Always disclose other prescriptions or supplements.
- • Do Not Share: Prescription-only product. Not for use by others.
When to Seek Medical AdviceReport any unusual or severe reactions to your healthcare provider immediately.
Cost of Synapsin® RG3 Nasal Spray
The cost of Synapsin® RG3 Nasal Spray typically ranges from $100 to $300 per month, depending on your dosage, treatment frequency, and personalized cognitive health needs. As a compounded therapy, Synapsin® is prepared with clinical precision, purity, and effectiveness at Rock Ridge Pharmacy.
Factors such as the complexity of your treatment plan and compounding fees contribute to the final price. Unlike mass-produced supplements, Synapsin® provides targeted neurological support for brain fog, memory, and focus through pharmacist-guided compounding.
For a personalized price quote or consultation, please call (201) 444-4190 or email info@rockridgepharmacy.com .

Why Rock Ridge Pharmacy for Synapsin® RG3 Compounding?
- Customized formulations tailored to your cognitive health needs, including brain fog, memory, and recovery support.
- USP <795> & <800> compliant lab ensuring pharmaceutical-grade purity, safety, and precision dosing.
- Collaborative care — pharmacists work with your provider to align Synapsin® therapy with clinical goals.
Every Synapsin® prescription is prepared under strict protocols in our cleanroom. We ensure each formulation is safe, effective, and customized for your neurological wellness plan.
Patients receive personalized pharmacist support, including guidance on usage, monitoring, and dose adjustments—helping you achieve optimal cognitive outcomes.
FAQS about Synapsin® RG3 Nasal Spray
What is Synapsin® RG3 Nasal Spray?
Synapsin® is a pharmacist-compounded nasal spray combining Ginsenoside Rg3, Nicotinamide Riboside (Vitamin B3), and Methylcobalamin (Vitamin B12). It’s designed to support cognitive function by reducing neuroinflammation, boosting brain energy, and promoting neuronal regeneration.
How does Synapsin® work?
The active ingredients target neurological pathways: Ginsenoside Rg3 regulates microglial activity, Nicotinamide Riboside enhances NAD+ and mitochondrial energy production, and Methylcobalamin supports nerve health and neurotransmitter synthesis.
Who can benefit from Synapsin®?
Patients with brain fog, cognitive decline, memory loss, post-viral fatigue, traumatic brain injury (TBI) recovery, neurodegenerative diseases such as Alzheimer’s, Parkinson’s, or MS, and stress-related cognitive fatigue may benefit from Synapsin®.
How is Synapsin® administered?
It is delivered via nasal spray for rapid absorption through the nasal mucosa directly into the brain. Typical use is once or twice daily, as directed by your provider.
Can I adjust my Synapsin® dosage on my own?
No. Dosage adjustments should only be made under the supervision of your healthcare provider or compounding pharmacist to ensure safety and effectiveness.
How should Synapsin® be stored?
Store Synapsin® in the refrigerator. Allow it to reach room temperature before use. When traveling, keep it in a cooler with an ice pack to maintain stability.
Is Synapsin® covered by insurance?
Most insurance plans do not cover compounded medications like Synapsin®. However, documentation may be provided for HSA/FSA reimbursement purposes.
How much does Synapsin® cost?
Costs typically range from $100–$300 per month, depending on your dosage, compounding requirements, and treatment plan at Rock Ridge Pharmacy.
What are the possible side effects of Synapsin®?
Synapsin® is usually well tolerated. Mild side effects may include nasal irritation, post-nasal drip, or headaches, which are generally temporary.
How long does it take to see results?
Some patients notice improved focus and mental clarity within days, while others may take a few weeks depending on individual response and treatment protocol.
Is Synapsin® safe for long-term use?
Yes. With provider supervision and regular follow-ups, Synapsin® can be used safely long-term, with adjustments as needed.
Can Synapsin® be combined with other cognitive supplements or medications?
Yes. Synapsin® is often part of integrative treatment plans. Always consult your provider and Rock Ridge Pharmacy before combining therapies.
Do I need a prescription for Synapsin®?
Yes. Synapsin® is a custom-compounded medication that requires a prescription from your licensed healthcare provider.
How can my provider send a prescription to Rock Ridge Pharmacy?
Providers can e-scribe to “Rock Ridge Pharmacy,” fax to 201-444-2698, or call us at 201-444-4190. For assistance, they may also email us.
How can I contact Rock Ridge Pharmacy about Synapsin®?
You can call 201-444-4190, email info@rockridgepharmacy.com, or visit our Contact Us page for more information.
Ways to Send In Prescriptions for Synapsin® RG3 Nasal Spray

1. Fax
Write a prescription on a prescription pad and fax over to 201-444-2698
We'll take care of the rest!

2. E-Scribe
E-Rx (E-scribe) to “Rock Ridge Pharmacy”
Make sure our address is 191 Rock Rd, Glen Rock, NJ 07452.

3. Call
- Call in your prescription to
- 201-444-4190.
We want to make sure it's as easy as possible for our patients!

4. Telemedicine
Rock Ridge Pharmacy, in partnership with Physician 360, offers convenient on-demand telemedicine consultations for DMSA detoxification and other conditions.