Ketotifen and Cromolyn
Compounded Ketotifen & Cromolyn Sodium – Mast Cell Stabilizers for MCAS & Mastocytosis
Understanding Mast Cell Disorders
Mast cells are immune cells in the skin, gut, lungs, and connective tissues that release histamine, prostaglandins, and leukotrienes. In Mast Cell Activation Syndrome (MCAS), mastocytosis, and Hereditary Alpha Tryptasemia (HAT), they become overactive, causing flushing, hives, gastrointestinal issues, breathing problems, brain fog, and anaphylaxis. Rock Ridge Pharmacy compounds Ketotifen and Cromolyn Sodium to stabilize mast cells, relieve symptoms, and support patients in Bergen County and throughout New Jersey.
MCAS, Mastocytosis, and HAT – Treated with Compounded Ketotifen & Cromolyn Sodium
Mast Cell Activation Syndrome (MCAS)
Mast Cell Activation Syndrome (MCAS) occurs when mast cells release excessive chemical mediators despite normal cell counts, causing widespread allergic-type symptoms across multiple organ systems. MCAS treatment often combines lifestyle adjustments, antihistamines, and mast cell stabilizers such as Ketotifen or Cromolyn Sodium, custom-compounded at Rock Ridge Pharmacy for precision dosing and reduced triggers.
Mastocytosis
Mastocytosis is characterized by an abnormal increase in mast cell numbers, often due to genetic mutations. These cells may infiltrate the skin, bone marrow, liver, spleen, and gastrointestinal tract, leading to persistent allergic symptoms. Our compounded Ketotifen and Cromolyn Sodium formulations are designed to minimize excipients and improve tolerability for mastocytosis patients.
Hereditary Alpha Tryptasemia (HAT)
Hereditary Alpha Tryptasemia (HAT) is a hereditary condition marked by elevated baseline tryptase levels, leading to mast cell overactivity and chronic allergy-like symptoms. While there is no cure, symptom control is often achieved through trigger avoidance and personalized medication regimens — including compounded mast cell stabilizers when appropriate.
How Ketotifen and Cromolyn Sodium Work
- Ketotifen and Cromolyn Sodium are mast cell stabilizers used in the treatment of Mast Cell Activation Syndrome (MCAS), mastocytosis, and Hereditary Alpha Tryptasemia (HAT). They work by preventing mast cells from releasing inflammatory mediators such as histamine, prostaglandins, and leukotrienes, which are responsible for allergic and inflammatory symptoms. Ketotifen provides dual benefits — mast cell stabilization and H₁ histamine receptor blocking — offering both prevention and symptom relief. Cromolyn Sodium focuses solely on mast cell stabilization, is non-sedating, and safe for long-term daily use.
Compounded Ketotifen Capsules at Rock Ridge Pharmacy
Ketotifen is a dual-action mast cell stabilizer and H₁ antihistamine used to manage Mast Cell Activation Syndrome (MCAS), mastocytosis, and other allergic or inflammatory conditions. While available in other countries as oral capsules, Ketotifen is not commercially available in the U.S. for systemic use—making compounding essential for patients who require this therapy.
Ketotifen Benefits:
- Stabilizes mast cells to prevent excessive mediator release
- Blocks H₁ histamine receptors to reduce allergy symptoms
- Helps control flares of itching, hives, swelling, and inflammation
- Can be tailored to sensitive patients, including those with excipient allergies
- Supports both systemic and gastrointestinal mast cell disorder
Compounded Ketotifen Dosage Forms at Rock Ridge Pharmacy:
- Capsules – Custom strengths including 0.5 mg, 1 mg, and 2 mg, prepared for precise patient dosing
- Alcohol-Free Liquid – Specially compounded for children, adults with swallowing difficulties, or patients sensitive to additives
How It Works:
Compounded Ketotifen works by stabilizing mast cell membranes to reduce calcium-dependent degranulation, preventing the release of inflammatory mediators such as histamine and leukotrienes. It also blocks H₁ histamine receptors, directly reducing allergic responses and improving symptom control. When compounded in custom capsules or alcohol-free liquids, Ketotifen provides personalized, well-tolerated therapy for patients in Bergen County and across New Jersey with mast cell disorders.
Compounded Cromolyn Sodium Capsules at Rock Ridge Pharmacy
Cromolyn Sodium is a non-sedating mast cell stabilizer commonly prescribed for Mast Cell Activation Syndrome (MCAS), mastocytosis, and allergic gastrointestinal disorders. It works by preventing the release of inflammatory mediators that cause allergic symptoms, making it a trusted long-term management option for sensitive patients.
Cromolyn Sodium Benefits:
- Non-sedating, allowing for clear mental function
- Helps control allergic and inflammatory symptoms
- Safe for long-term use due to minimal systemic absorption
- Supports management of both systemic and gastrointestinal mast cell disorders
Cromolyn Sodium Dosage Forms at Rock Ridge Pharmacy:
- Capsules – Most commonly 100 mg and 200 mg, with custom strengths available
- Trigger-Free Liquid – Additive-free and alcohol-free formulation, ideal for patients in Bergen County and across New Jersey with sensitivities or swallowing difficulties
How It Works:
Cromolyn Sodium stabilizes mast cell membranes, blocking the release of histamine, prostaglandins, and leukotrienes that drive allergic and inflammatory responses. With minimal absorption into the bloodstream, it delivers a strong safety profile and reliable symptom control for mast cell disorders.
Compounded Ketotifen vs. Cromolyn Sodium: Benefits, Dosage Forms, and Key Differences
| Category | Compounded Ketotifen | Compounded Cromolyn Sodium |
|---|---|---|
| Pharmacologic Action | Mast cell stabilizer + H₁ antihistamine | Non-sedating mast cell stabilizer |
| Primary Uses | MCAS, mastocytosis, allergic skin/respiratory symptoms | MCAS, mastocytosis, allergic GI disorders, asthma |
| Unique Benefit | H₁ blockade for added relief (itching, hives, swelling) | Minimal systemic absorption; well-tolerated long-term |
| Dosage Forms |
Capsules 0.5 mg1 mg2 mg
Alcohol-free liquid (custom strengths available) |
Capsules 100 mg200 mg
Trigger-free liquid (custom strengths available) |
Possible Side Effects of Compounded Ketotifen and Cromolyn Sodium
At Rock Ridge Pharmacy, our custom-compounded Ketotifen and Cromolyn Sodium are designed for patients managing Mast Cell Activation Syndrome (MCAS), mastocytosis, and related allergic conditions. While both medications are generally well-tolerated, some patients in Bergen County and across New Jersey may experience mild and temporary side effects.
Compounded Ketotifen — Potential Side Effects:
- Drowsiness or mild sedation, especially during initial use
- Dry mouth or throat
- Mild weight gain with long-term therapy
- Occasional stomach upset, nausea, or digestive discomfort
Compounded Cromolyn Sodium — Potential Side Effects:
-
Headache or lightheadedness
-
Mild gastrointestinal upset, including nausea or diarrhea
-
Throat irritation with oral liquid formulations
-
Rare skin rash or mild cough
Most side effects resolve as the body adjusts to treatment. Patients should promptly report persistent or severe symptoms to their healthcare provider for evaluation and possible dose adjustment. Our pharmacists are available to provide guidance and ensure your compounded mast cell stabilizer is both safe and effective for long-term use.
Proper Storage for Compounded Ketotifen and Cromolyn Sodium
At Rock Ridge Pharmacy, we prepare compounded Ketotifen and Cromolyn Sodium with the highest quality standards to ensure effectiveness for patients managing mast cell disorders in Bergen County and across New Jersey. Proper storage is essential to maintain each medication’s potency, safety, and stability.
Storage Guidelines:
- Temperature: Store at controlled room temperature (68°F–77°F / 20°C–25°C) unless otherwise directed by your pharmacist.
- Light & Moisture Protection: Keep in a cool, dry location away from direct sunlight, heat sources, and high humidity.
- Original Container: Maintain medications in their original, tightly sealed, labeled containers to prevent contamination.
- Special Instructions for Liquids: Some compounded liquid formulations may require refrigeration—always check your prescription label for exact directions.
- Safety Precautions: Store out of reach of children and pets to prevent accidental ingestion.
Important: Always follow the specific storage instructions provided with your prescription, as stability and shelf life can vary based on whether your compounded medication is prepared as a capsule or liquid.
Pharmacist-Recommended Supplements to Support Ketotifen & Cromolyn Therapy
To further support your compounded Ketotifen or Cromolyn Sodium therapy, Rock Ridge Pharmacy recommends targeted supplements available through our online shop. Vitamin D3 5,000 IU + K2 promotes immune balance, bone health, and calcium regulation, while Reacted Zinc supports skin integrity and overall immune resilience. For anti-inflammatory and cardiovascular benefits, Orthomega® 820 provides high-quality EPA and DHA omega-3s. Gut and immune health can be further enhanced with Ortho Biotic Capsules, which deliver beneficial probiotics and prebiotics.
These pharmacist-selected supplements are designed to complement mast cell stabilizer therapy, helping optimize symptom control and overall well-being for patients in Bergen County and throughout New Jersey.
Why Choose Rock Ridge Pharmacy for Compounded Ketotifen & Cromolyn Sodium?
Customized Ketotifen & Cromolyn Formulations: At Rock Ridge Pharmacy, we compound Ketotifen and Cromolyn Sodium into oral capsules or trigger-free liquid formulations—tailored to your specific mast cell disorder, symptom profile, and provider’s prescription. Whether you’re managing Mast Cell Activation Syndrome (MCAS), mastocytosis, or allergic gastrointestinal conditions, our personalized dosing ensures maximum tolerability and effectiveness.
USP <800>-Compliant Quality: All Ketotifen and Cromolyn Sodium formulations are prepared in our USP <795>/<800>-compliant cleanroom, following strict pharmaceutical-grade purity, safe handling, and precise dosing protocols. We meet or exceed national compounding standards to ensure each prescription is safe, stable, and effective.
Collaborative Pharmacist Support: Our expert pharmacists work directly with your healthcare provider to customize each formulation to your needs. We provide patient education, adjust formulations based on tolerance, and offer ongoing clinical guidance—helping you achieve better symptom control while minimizing side effects.
Cost of Compounded Ketotifen & Cromolyn Sodium at Rock Ridge Pharmacy
The price of compounded Ketotifen or Cromolyn Sodium at Rock Ridge Pharmacy in Glen Rock, NJ varies based on formulation (capsules or trigger-free liquid), dosage strength, and the level of customization required. Each prescription is individually prepared in our USP <795>/<800>-compliant compounding lab using pharmaceutical-grade ingredients to ensure maximum purity, safety, and effectiveness.
These medications are commonly prescribed for Mast Cell Activation Syndrome (MCAS), mastocytosis, and hereditary alpha tryptasemia, and we work closely with your provider to match dosing and formulation to your exact needs. Pricing reflects the personalized nature of compounded mast cell stabilizers and the expertise of our compounding pharmacists.
For an exact quote on compounded Ketotifen or Cromolyn Sodium, call 201-444-4190 or email info@rockridgepharmacy.com.
Pharmacist’s Role in Compounded Ketotifen & Cromolyn Sodium Therapy
Pharmacists play a vital role in ensuring the safety and effectiveness of compounded Ketotifen and Cromolyn Sodium therapies. At Rock Ridge Pharmacy, our compounding pharmacists review each prescription to confirm accurate dosing, optimal formulation, and alignment with your individual treatment goals. Whether your medication is compounded as a capsule or a trigger-free liquid, our team manages every stage—from pharmaceutical-grade ingredient sourcing and precise preparation to quality assurance and patient education.
We also provide personalized guidance on proper storage, potential drug or supplement interactions, and symptom monitoring. When necessary, we work directly with your healthcare provider to adjust formulations or dosing for improved tolerability and results. Our goal is to deliver mast cell stabilizer therapy that is safe, effective, and personalized for patients in Bergen County and throughout New Jersey.
FAQS About Compounded Ketotifen & Cromolyn Sodium at Rock Ridge Pharmacy
What is compounded Ketotifen used for?
Compounded Ketotifen is a dual-action mast cell stabilizer and H₁ antihistamine used to manage Mast Cell Activation Syndrome (MCAS), mastocytosis, and other allergic or inflammatory conditions. It helps reduce histamine release and control symptoms such as itching, hives, and swelling.
What is compounded Cromolyn Sodium used for?
Compounded Cromolyn Sodium is a non-sedating mast cell stabilizer often prescribed for MCAS, mastocytosis, and allergic gastrointestinal disorders. It works by preventing the release of inflammatory mediators, making it a preferred long-term treatment option for sensitive patients.
Why choose compounded formulations over commercially available products?
Commercial options may contain additives, dyes, or sweeteners that can trigger symptoms in mast cell patients. Compounding allows for customized strengths and trigger-free formulations, tailored to your provider’s exact specifications.
What dosage forms are available at Rock Ridge Pharmacy?
At Rock Ridge Pharmacy, we offer compounded Ketotifen in capsule form—commonly available in 0.5 mg, 1 mg, and 2 mg strengths, with custom dosages available upon request—as well as an alcohol-free, dye-free Ketotifen liquid for patients with sensitivities. We also prepare compounded Cromolyn Sodium in capsules, most often 100 mg and 200 mg (custom strengths available), and in a trigger-free, additive-free, alcohol-free liquid ideal for patients requiring the purest possible formulation.
Are compounded Ketotifen and Cromolyn Sodium safe for long-term use?
Yes—both are generally well-tolerated when prescribed by your healthcare provider. Cromolyn Sodium has minimal systemic absorption, and Ketotifen has a long history of safe use in mast cell disorders. Your pharmacist will monitor for any potential side effects.
How much do compounded Ketotifen and Cromolyn Sodium cost?
Pricing varies based on dosage form, strength, and level of customization. For a personalized quote, call 201-444-4190 or email info@rockridgepharmacy.com.
How long does it take for Ketotifen or Cromolyn Sodium to work?
Symptom relief timelines vary. Some patients notice improvement within a few days, while others may require several weeks of consistent use to achieve optimal results—especially with Cromolyn Sodium, which works best with regular dosing.
Can Ketotifen or Cromolyn Sodium be taken with other medications?
Yes, but potential drug interactions should be reviewed. Always inform your pharmacist and healthcare provider about all prescription drugs, supplements, and over-the-counter medications you are taking.
Do these medications cause drowsiness?
Ketotifen may cause mild sedation in some patients, particularly when starting treatment. Cromolyn Sodium is non-sedating and generally does not affect alertness.
How should I store Ketotifen and Cromolyn Sodium?
Most compounded mast cell stabilizers should be stored at controlled room temperature (68°F–77°F), away from heat, moisture, and direct light. Certain liquid formulations may require refrigeration—check your prescription label for exact instructions.
Can children take compounded Ketotifen or Cromolyn Sodium?
Yes—both medications can be prescribed for pediatric patients with mast cell disorders, but dosing must be carefully calculated by a healthcare provider. Compounding allows for child-friendly strengths and alcohol-free liquids.
Do I need a prescription for compounded Ketotifen or Cromolyn Sodium?
Yes—a prescription from a licensed healthcare provider is required. Compounded medications are made specifically for your needs and are not available over the counter.
Are there dietary restrictions while taking mast cell stabilizers?
While no universal restrictions apply, many patients with mast cell disorders follow a low-histamine diet to reduce flare-ups. Your pharmacist or provider can help you coordinate medications with your diet for best results.
Ways to Send In Prescriptions for Compounded Ketotifen and Cromolyn
1. Fax
Write a prescription on a prescription pad and fax over to 201-444-2698
We'll take care of the rest!
2. E-Scribe
E-Rx (E-scribe) to “Rock Ridge Pharmacy”
Make sure our address is 191 Rock Rd, Glen Rock, NJ 07452.
3. Call
- Call in your prescription to
- 201-444-4190.
We want to make sure it's as easy as possible for our patients!
4. Telemedicine
Rock Ridge Pharmacy, in partnership with Physician 360, offers convenient on-demand telemedicine consultations for Ketotifen and Cromolyn