Ketotifen and Cromolyn
Compounded Ketotifen & Cromolyn Sodium – Mast Cell Stabilizers for MCAS & Mastocytosis
Understanding Mast Cell Disorders
Mast cells are immune cells in the skin, gut, lungs, and connective tissues that release histamine, prostaglandins, and leukotrienes. In Mast Cell Activation Syndrome (MCAS), mastocytosis, and Hereditary Alpha Tryptasemia (HAT), they become overactive, causing flushing, hives, gastrointestinal issues, breathing problems, brain fog, and anaphylaxis. Rock Ridge Pharmacy compounds Ketotifen and Cromolyn Sodium to stabilize mast cells, relieve symptoms, and support patients in Bergen County and throughout New Jersey.
Compounded Ketotifen & Cromolyn for Mast Cell Disorders
MCAS
Mast Cell Activation Syndrome occurs when mast cells release excess mediators.
Symptoms may include flushing, hives, abdominal pain, or fatigue.
Management often combines trigger avoidance, antihistamines, and stabilizers such as Ketotifen or Cromolyn.
Mastocytosis
Mastocytosis results from increased mast cells in skin, bone marrow, or organs.
Patients may develop rashes, GI upset, or systemic flares.
Compounded Ketotifen and Cromolyn are available in capsules or alcohol-free liquids for improved tolerability.
HAT
Hereditary Alpha Tryptasemia is caused by extra copies of the tryptase gene.
Elevated levels can lead to allergy-like symptoms, joint issues, and connective tissue problems.
Management focuses on lifestyle strategies plus compounded mast cell stabilizers for relief.
How Ketotifen and Cromolyn Sodium Work
- Ketotifen and Cromolyn Sodium are mast cell stabilizers used in the treatment of Mast Cell Activation Syndrome (MCAS), mastocytosis, and Hereditary Alpha Tryptasemia (HAT). They work by preventing mast cells from releasing inflammatory mediators such as histamine, prostaglandins, and leukotrienes, which are responsible for allergic and inflammatory symptoms. Ketotifen provides dual benefits — mast cell stabilization and H₁ histamine receptor blocking — offering both prevention and symptom relief. Cromolyn Sodium focuses solely on mast cell stabilization, is non-sedating, and safe for long-term daily use.
Compounded Ketotifen vs. Cromolyn Sodium
| Category | Compounded Ketotifen | Compounded Cromolyn Sodium |
|---|---|---|
| Pharmacologic Action | Mast cell stabilizer + H₁ antihistamine | Non-sedating mast cell stabilizer |
| Primary Uses | MCAS, mastocytosis, allergic skin/respiratory symptoms | MCAS, mastocytosis, allergic GI disorders, asthma |
| Unique Benefit | H₁ blockade for added relief (itching, hives, swelling) | Minimal systemic absorption; well-tolerated long-term |
| Dosage Forms |
Capsules 0.5 mg1 mg2 mg
Alcohol-free liquid (custom strengths available) |
Capsules 100 mg200 mg
Trigger-free liquid (custom strengths available) |
Ketotifen is a dual-action mast cell stabilizer and H₁ antihistamine used to manage Mast Cell Activation Syndrome (MCAS), mastocytosis, and allergic conditions. Since it is not commercially available in the U.S., compounding ensures patients receive safe, customized therapy tailored to their needs.
Provides custom strengths, filler-free options, and formulations not otherwise available in the U.S.
Key Benefits
- Blocks H₁ histamine receptors to ease allergy symptoms
- Stabilizes mast cells to reduce mediator release
- Helps control itching, hives, swelling, and inflammation
- Suitable for sensitive patients, including excipient allergies
- Supports systemic & gastrointestinal mast cell disorders
Dosage Forms
- Capsules – Custom strengths 0.5 mg, 1 mg, 2 mg
- Alcohol-Free Liquid – Ideal for children, adults with swallowing difficulties, or those sensitive to additives
How Ketotifen Works
Ketotifen stabilizes mast cell membranes, preventing degranulation and reducing the release of histamine and leukotrienes. By blocking H₁ receptors, it decreases allergic responses and improves symptom control. Personalized compounding ensures accurate dosing and better tolerability for long-term mast cell disorder management.
Cromolyn Sodium is a non-sedating mast cell stabilizer commonly prescribed for Mast Cell Activation Syndrome (MCAS), mastocytosis, and allergic gastrointestinal disorders. Because oral forms are not commercially available in the U.S., Rock Ridge Pharmacy compounds Cromolyn into safe, customized therapies tailored to each patient.
Provides capsule and liquid options not sold commercially, with custom strengths, alcohol-free liquids, and additive-free formulations for sensitive patients.
Key Benefits
- Non-sedating, supports clear mental function
- Helps control allergic and inflammatory symptoms
- Safe for long-term use with minimal systemic absorption
- Effective for both systemic and gastrointestinal mast cell disorders
Dosage Forms
- Capsules – Common strengths 100 mg, 200 mg, with additional strengths available
- Trigger-Free Liquid – Alcohol-free, additive-free, ideal for children and sensitive patients
How Cromolyn Sodium Works
Cromolyn Sodium stabilizes mast cell membranes, preventing the release of histamine, prostaglandins, and leukotrienes that trigger allergic and inflammatory responses. With minimal absorption into the bloodstream, it delivers a strong safety profile and reliable long-term symptom control for patients managing mast cell disorders.
Potential Side Effects of Compounded Ketotifen & Cromolyn Sodium
Understanding what to expect during treatment with mast cell stabilizers.
Compounded Ketotifen — Side Effects
- Drowsiness or mild sedation, especially during initial use
- Dry mouth or throat
- Mild weight gain with long-term therapy
- Occasional stomach upset, nausea, or digestive discomfort
Compounded Cromolyn Sodium — Side Effects
- Headache or lightheadedness
- Mild gastrointestinal upset, including nausea or diarrhea
- Throat irritation with oral liquid formulations
- Rare skin rash or mild cough
Supplements for Mast Cell Stabilizer Therapy
To further support your compounded Ketotifen or Cromolyn Sodium therapy, Rock Ridge Pharmacy recommends targeted supplements available through our online shop. Vitamin D3 5,000 IU + K2 promotes immune balance, bone health, and calcium regulation, while Reacted Zinc supports skin integrity and overall immune resilience. For anti-inflammatory and cardiovascular benefits, Orthomega® 820 provides high-quality EPA and DHA omega-3s. Gut and immune health can be further enhanced with Ortho Biotic Capsules, which deliver beneficial probiotics and prebiotics.
These pharmacist-selected supplements are designed to complement mast cell stabilizer therapy, helping optimize symptom control and overall well-being for patients in Bergen County and throughout New Jersey.
Storage & Handling for Compounded Ketotifen and Cromolyn Sodium
Proper storage ensures potency, safety, and stability for patients managing mast cell disorders.
Why Choose Us for Compounded Ketotifen & Cromolyn Sodium?
- Customized Ketotifen & Cromolyn Formulations: At Rock Ridge Pharmacy, we prepare Ketotifen and Cromolyn Sodium as capsules or trigger-free liquids, tailored to your mast cell disorder, symptoms, and prescription. These personalized options support patients with MCAS, mastocytosis, and allergic gastrointestinal conditions.
USP <800>-Compliant Quality: All formulations are prepared in our USP <795>/<800> cleanroom using pharmaceutical-grade ingredients. Strict safety and dosing standards ensure each prescription is pure, stable, and effective.
Collaborative Pharmacist Support: Our pharmacists work directly with your provider to customize therapy, adjust formulations, and provide ongoing education—helping improve symptom control while reducing side effects.
Cost of Compounded Ketotifen & Cromolyn Sodium at Rock Ridge Pharmacy
Pricing varies based on formulation (capsules or trigger-free liquid), dosage strength, and level of customization. Each prescription is prepared in our USP <795>/<800>-compliant lab using pharmaceutical-grade ingredients for safety, purity, and effectiveness.
These mast cell stabilizers are commonly prescribed for Mast Cell Activation Syndrome (MCAS), mastocytosis, and hereditary alpha tryptasemia. Our pharmacists work closely with your provider to ensure dosing and formulation match your exact needs.
Pharmacist Support for Ketotifen & Cromolyn Sodium
Pharmacists play a vital role in the safe and effective use of compounded Ketotifen and Cromolyn Sodium. Each prescription is carefully reviewed to ensure accurate dosing, optimal formulation, and alignment with your treatment goals.
Our compounding team manages every step—from ingredient sourcing and preparation to quality checks and patient education. We provide guidance on proper storage, potential interactions, and symptom monitoring. When needed, we collaborate directly with your healthcare provider to adjust dosing or formulations for better results.
Our goal is to deliver safe, effective, and personalized mast cell stabilizer therapy for patients across Bergen County and New Jersey.
FAQS About Compounded Ketotifen & Cromolyn Sodium at Rock Ridge Pharmacy
What is compounded Ketotifen used for?
Compounded Ketotifen is a dual-action mast cell stabilizer and H₁ antihistamine used to manage Mast Cell Activation Syndrome (MCAS), mastocytosis, and other allergic or inflammatory conditions. It reduces histamine release and controls symptoms such as itching, hives, and swelling.
What is compounded Cromolyn Sodium used for?
Compounded Cromolyn Sodium is a non-sedating mast cell stabilizer often prescribed for MCAS, mastocytosis, and allergic gastrointestinal disorders. It prevents the release of inflammatory mediators, making it a preferred long-term treatment option for sensitive patients.
Why choose compounded formulations over commercial products?
Commercial options may contain dyes, additives, or sweeteners that can trigger symptoms in mast cell patients. Compounding allows for customized strengths and trigger-free formulations tailored to your provider’s specifications.
What dosage forms are available at Rock Ridge Pharmacy?
We offer compounded Ketotifen in capsules (commonly 0.5 mg, 1 mg, and 2 mg, with custom strengths available) and alcohol-free, dye-free liquid suspensions for sensitive patients. Compounded Cromolyn Sodium is available in 100 mg and 200 mg capsules, with custom strengths, and in a trigger-free, alcohol-free liquid formulation.
Are compounded Ketotifen and Cromolyn Sodium safe for long-term use?
Yes—both are generally well-tolerated when prescribed by your provider. Cromolyn Sodium has minimal systemic absorption, and Ketotifen has a long history of safe use in mast cell disorders. Pharmacist monitoring ensures ongoing safety.
How long does it take for Ketotifen or Cromolyn Sodium to work?
Timelines vary. Some patients notice symptom relief in days, while others require several weeks of consistent use—particularly with Cromolyn Sodium, which works best with regular dosing.
Do these medications cause drowsiness?
Ketotifen may cause mild sedation, especially when first starting treatment. Cromolyn Sodium is non-sedating and does not typically affect alertness.
Can Ketotifen or Cromolyn Sodium be taken with other medications?
Yes, but potential drug interactions should always be reviewed. Inform your provider and pharmacist about all medications, supplements, and over-the-counter products you take.
How should I store Ketotifen and Cromolyn Sodium?
Store at controlled room temperature (68°F–77°F), away from heat, light, and moisture. Some liquid formulations may require refrigeration—check your prescription label for instructions.
Can children take compounded Ketotifen or Cromolyn Sodium?
Yes—if prescribed by a pediatrician. Compounding allows for child-friendly strengths and alcohol-free liquids, ensuring safer dosing for pediatric patients.
Are compounded mast cell stabilizers safe for sensitive patients?
Yes. Compounding removes dyes, fillers, and additives that often trigger reactions in mast cell patients, providing a purer formulation tailored to individual sensitivities.
Do I need a prescription for compounded Ketotifen or Cromolyn Sodium?
Yes—a valid prescription from a licensed healthcare provider is required. Compounded medications are made specifically for your needs and are not available over the counter.
How can my provider send a prescription to Rock Ridge Pharmacy?
Providers can e-scribe to “Rock Ridge Pharmacy,” fax to 201-444-2698, or call 201-444-4190. They may also email info@rockridgepharmacy.com for assistance.
How much do compounded Ketotifen and Cromolyn Sodium cost?
Pricing depends on strength, dosage form, and customization. Contact us at 201-444-4190 or info@rockridgepharmacy.com for a personalized quote.
How can I contact Rock Ridge Pharmacy for more information?
Call 201-444-4190, email info@rockridgepharmacy.com, or visit our Contact Us page for more information.
Ways to Send In Prescriptions for Compounded Ketotifen and Cromolyn
1. Fax
Write a prescription on a prescription pad and fax over to 201-444-2698
We'll take care of the rest!
2. E-Scribe
E-Rx (E-scribe) to “Rock Ridge Pharmacy”
Make sure our address is 191 Rock Rd, Glen Rock, NJ 07452.
3. Call
- Call in your prescription to
- 201-444-4190.
We want to make sure it's as easy as possible for our patients!
4. Telemedicine
Rock Ridge Pharmacy, in partnership with Physician 360 offers convenient on-demand telemedicine consultations