Customized Care • Prescription Required

Sexual Wellness Compounding

Rock Ridge Pharmacy compounds Trimix and Quadmix—custom injectable formulations that promote healthy blood flow to the penis and support erectile function. Each prescription is carefully prepared to help men achieve stronger, longer-lasting erections with safe, pharmacist-guided precision.

What Are Trimix and Quadmix Injections?

Trimix and Quadmix compounded injections at Rock Ridge Pharmacy in Glen Rock, NJ

Trimix and Quadmix are prescription injectable medications formulated to improve blood flow to the penis, helping men achieve and maintain firm erections. These therapies are compounded under the direction of a prescriber for personalized erectile dysfunction (ED) treatment.

Each formulation works by directly relaxing and dilating blood vessels in penile tissue, enhancing circulation and response. Rock Ridge Pharmacy compounds these injections with precise concentrations to match each patient’s medical profile and tolerance.

Compounded Trimix and Quadmix injections are prescription-only and prepared in our USP <795>/<800> compliant lab to ensure quality, sterility, and safety for every dose.

Learn more about AUA Erectile Dysfunction Guidelines and USP Sterile Compounding Standards.

Trimix & Quadmix Components

Trimix Components

  • Alprostadil: A synthetic form of prostaglandin E1 that relaxes smooth muscle tissue and dilates blood vessels for improved blood flow.
  • Papaverine: A vasodilator that relaxes smooth muscles in the blood vessels, increasing circulation to the penis.
  • Phentolamine: An alpha-blocker that widens blood vessels by blocking alpha receptors, further enhancing blood flow.

Quadmix Components

  • Trimix Base: Combination of Alprostadil, Papaverine, and Phentolamine.
  • Atropine: Enhances relaxation by inhibiting nervous system receptors responsible for muscle control, making Quadmix an excellent option for men requiring a stronger formulation.

Both Trimix and Quadmix are compounded under USP <795>/<800> sterile standards at Rock Ridge Pharmacy, ensuring purity, accuracy, and consistency in every injection.

Who Can Benefit from Trimix and Quadmix?

Non-Responders to Oral Medications

Ideal for men who do not respond adequately to sildenafil (Viagra®) or tadalafil (Cialis®).

Sensitive to Oral Side Effects

Suitable for men who experience headaches, flushing, or gastrointestinal upset from oral ED medications.

Underlying Health Conditions

Effective for men whose erectile dysfunction is linked to:

• Diabetes
• Cardiovascular disease
• Prostate surgery
• Neurological disorders

Compounded Trimix and Quadmix injections are personalized to address the specific cause of ED. Each formulation is prepared under USP <795>/<800> standards for precision, safety, and optimal patient outcomes.

How Are Trimix and Quadmix Injections Administered?

Trimix and Quadmix injections are administered directly into the side of the penis (corpora cavernosa) using a small, fine needle.

Step-by-Step Instructions

  1. Preparation:
    Wash your hands thoroughly.
    Use an alcohol swab to clean both the vial and the injection site.
  2. Draw the Medication:
    Using an insulin syringe, draw the prescribed dose of Trimix or Quadmix exactly as instructed.
  3. Injection:
    Hold the penis steady and inject at a 90-degree angle into the side of the shaft (corpora cavernosa).
    Avoid veins and do not inject into the top or bottom of the penis.
  4. Post-Injection:
    Apply gentle pressure to the injection site for 1–2 minutes to reduce bruising.
    Dispose of the syringe safely in a designated sharps container.

Our pharmacists provide individualized training and guidance to help patients perform injections safely and confidently at home. For any questions or follow-up care, contact Rock Ridge Pharmacy for professional support.

Supplements to Support Sexual Wellness

Our pharmacists may recommend these supplements to support your men’s hormone health, improve circulation, and enhance the efficacy of Trimix & Quadmix therapy.

Sexual Wellness Supplements – Rock Ridge Pharmacy
  • L-Arginine 3 g – supports nitric-oxide mediated blood flow.
  • Red Ginseng 500 mg – may improve sexual performance and stamina.
  • Vitamin D₃ (5,000 IU) – supports vascular health and hormone balance.
  • Tribulus Terrestris Extract – a botanical aid for libido and male sexual health.
  • Zinc Picolinate 30 mg – supports testosterone production and reproductive function.

These supplements are adjunctive recommendations only. They do not replace prescription injectable therapies and should be reviewed with your healthcare provider.

Prescription Required

What Are the Side Effects of Trimix and Quadmix Injections?

While generally safe, Trimix and Quadmix may have some side effects. Proper technique and guidance from your pharmacist or prescriber can help minimize these risks.

  • Mild discomfort at the injection site. This usually resolves quickly after administration.
  • Prolonged erections (priapism). Seek immediate medical attention if an erection lasts longer than 4 hours.
  • Scar tissue formation. Can occur with frequent or improper injection technique over time.

Always follow your prescribed dosage and injection schedule to minimize potential side effects. Consult your Rock Ridge Pharmacy pharmacist for guidance on safe self-administration and ongoing monitoring.

Storage & Safety Information for Trimix and Quadmix Injections

Storage Guidelines

Trimix and Quadmix injections should be stored in the refrigerator at 36°F–46°F (2°C–8°C) to maintain potency. Do not freeze. If using a travel vial, keep it in an insulated container with a cold pack during transport.

Before injecting, allow the vial to reach room temperature for a few minutes. Avoid exposing the medication to heat, direct sunlight, or excessive agitation. Always keep vials tightly sealed and out of reach of children and pets.

Questions about storage, expiration, or proper handling? Call 201-444-4190 or email info@rockridgepharmacy.com .

Safety Precautions

Use only as prescribed. Do not adjust your dose without consulting your provider. Excessive dosing can cause priapism (erections lasting longer than 4 hours), which requires emergency care.

Rotate injection sites. Alternate sides of the penis to minimize scar tissue or fibrosis. Never inject into visible veins or the top or bottom of the shaft.

Proper disposal: Place used syringes in a puncture-proof sharps container. Do not throw loose needles in household trash. Rock Ridge Pharmacy can guide you on safe disposal options.

Disclaimer: This information is for educational purposes only and does not replace medical advice. Always consult your healthcare provider before making any changes to your Trimix or Quadmix therapy.

Cost of Trimix & Quadmix Injections

Below is a pricing overview of compounded Trimix and Quadmix formulations available at Rock Ridge Pharmacy. All injections are prepared in our USP <795>/<800>-compliant compounding lab for accuracy, purity, and patient safety.

Quadmix 1 mL Vials

Formula Concentration Cost
Alprostadil / Papaverine / Phentolamine / Atropine20 mcg / 30 mg / 2 mg / 100 mcg per mL$75.00
Alprostadil / Papaverine / Phentolamine / Atropine30 mcg / 30 mg / 3 mg / 200 mcg per mL$75.00
Alprostadil / Papaverine / Phentolamine / Atropine60 mcg / 30 mg / 3 mg / 200 mcg per mL$75.00

Trimix 1 mL Vials

Formula Concentration Cost
Alprostadil / Papaverine / Phentolamine20 mcg / 30 mg / 2 mg per mL$75.00
Alprostadil / Papaverine / Phentolamine30 mcg / 30 mg / 3 mg per mL$75.00
Alprostadil / Papaverine / Phentolamine20 mcg / 7.5 mg / 0.25 mg per mL$75.00
Alprostadil / Papaverine / Phentolamine75 mcg / 15 mg / 0.5 mg per mL$75.00
Alprostadil / Papaverine / Phentolamine150 mcg / 30 mg / 2 mg per mL$75.00

Trimix 5 mL Vials

Formula Concentration Cost
Alprostadil / Papaverine / Phentolamine40 µg / 30 mg / 2 mg per mL$180.00

*Prices may vary depending on formulation and prescribed strength. Please contact Rock Ridge Pharmacy at (201) 444-4190 for the most up-to-date pricing and availability.

Pharmacy compounding area for Trimix and Quadmix preparation at Rock Ridge Pharmacy

Why Rock Ridge Pharmacy for Trimix & Quadmix Injections?

  • Customized concentrations of Alprostadil, Papaverine, Phentolamine, and Atropine for precise response and duration.
  • Pharmacist-compounded formulations ensure accuracy, sterility, and consistent performance.
  • Private consultation available for dosing adjustments, safe injection technique, and therapy optimization.

Our pharmacists collaborate with prescribers to personalize every Trimix or Quadmix prescription — ensuring it’s clinically effective, safely administered, and tailored to your health goals.

Contact Rock Ridge Pharmacy

FAQs About Sexual Wellness at Rock Ridge Pharmacy

What are Trimix and Quadmix injections?

Trimix and Quadmix are prescription injectable medications that improve erectile function by increasing blood flow to the penis. Each formulation combines vasodilators such as Alprostadil, Papaverine, Phentolamine, and, in Quadmix, Atropine for enhanced response.

How do Trimix and Quadmix work?

These medications act directly on the smooth muscle tissue of the penis, relaxing blood vessels to allow increased blood flow. The result is a firm, natural erection achieved independently of sexual stimulation in most cases.

What is the difference between Trimix and Quadmix?

Both contain Alprostadil, Papaverine, and Phentolamine. Quadmix adds Atropine, which provides additional relaxation of smooth muscles for men who require a stronger or longer-lasting effect.

Who can benefit from these injections?

Trimix and Quadmix are ideal for men who do not respond well to oral ED medications, experience side effects from pills, or have medical conditions such as diabetes, cardiovascular disease, prostate surgery history, or neurological disorders.

How are Trimix and Quadmix injections administered?

They are injected directly into the side of the penis (corpora cavernosa) using a fine needle. Our pharmacists provide detailed training on proper technique, dosage, and safety during initial consultations.

Are the injections painful?

Most patients report only mild discomfort or a brief sting at the injection site. With correct technique and rotation of injection areas, pain and bruising are minimal.

How long do the effects last?

The erection typically develops within 5 to 15 minutes and lasts 30 to 90 minutes depending on dose, medication strength, and individual response.

What are the possible side effects?

Potential side effects include mild pain at the injection site, bruising, or small nodules. A prolonged erection lasting more than 4 hours (priapism) is a medical emergency and requires immediate care.

How should Trimix and Quadmix be stored?

Keep vials refrigerated between 36°F and 46°F (2°C–8°C). Do not freeze. Use an insulated travel container with a cold pack when transporting the medication.

How long does a vial last?

Most vials last 30 to 90 days depending on frequency of use and dosage. Your pharmacist can estimate usage and provide refill reminders.

Can Trimix and Quadmix be used with oral ED medications?

Generally, they should not be combined with PDE5 inhibitors (such as Viagra or Cialis) unless approved by your prescriber, as this can increase risk of low blood pressure or prolonged erections.

Do I need a prescription?

Yes. Both Trimix and Quadmix are compounded prescription medications that require a valid prescription from a licensed healthcare provider.

How can I order Trimix or Quadmix from Rock Ridge Pharmacy?

Providers can e-prescribe directly to “Rock Ridge Pharmacy” or fax to 201-444-2698. Patients may call (201) 444-4190 or email info@rockridgepharmacy.com for assistance.

Are compounded injections sterile and safe?

Yes. Rock Ridge Pharmacy prepares all injections under USP <797> sterile compounding standards using pharmaceutical-grade ingredients to ensure safety and accuracy.

Can I travel with Trimix or Quadmix?

Yes. Store the medication in a travel cooler with a cold pack and keep it with your prescription label when traveling. Avoid leaving it in hot cars or direct sunlight.

Ways to Send Prescriptions

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1. Fax

Write a prescription on a pad and fax it to
201-444-2698

We’ll take care of the rest!

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2. E-Scribe

E-Rx (E-scribe) to “Rock Ridge Pharmacy”

Confirm our address:
191 Rock Rd, Glen Rock, NJ 07452

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3. Call

Call in your prescription to
201-444-4190

We make it easy for our patients!

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4. Telemedicine

Rock Ridge Pharmacy partners with Physician 360 for on-demand telemedicine consultations.

Start your telemedicine visit now