What are Trimix and Quadmix injections?
Trimix and Quadmix are prescription injectable medications that improve erectile function by increasing blood flow to the penis. Trimix combines alprostadil, papaverine, and phentolamine. Quadmix adds atropine for men who need a stronger response.
How do Trimix and Quadmix work?
These medications act directly on the smooth muscle tissue of the penis, relaxing blood vessels to allow more blood flow. In most men, an erection develops within minutes of the injection.
What is the difference between Trimix and Quadmix?
Both contain alprostadil, papaverine, and phentolamine. Quadmix adds atropine, which may help men who need a stronger or longer-lasting effect than Trimix provides.
Who can benefit from Trimix and Quadmix injections?
They may help men who do not respond well to oral ED medications like sildenafil or tadalafil, have side effects from pills, or have ED linked to diabetes, cardiovascular disease, prostate surgery, or neurological conditions.
Where are Rock Ridge Pharmacy’s Trimix and Quadmix compounded?
Our Trimix and Quadmix are prepared by a state-licensed 503A compounding pharmacy. 503A pharmacies compound medications for individual patients based on a valid prescription and follow USP <797> standards for sterile injections.
Are Trimix and Quadmix FDA-approved?
No. Compounded medications are not FDA-approved. The FDA does not review them for safety, effectiveness, or quality before they are dispensed. They are prepared by a licensed 503A pharmacy under the direction of a licensed prescriber.
How are Trimix and Quadmix injections administered?
They are injected into the side of the penis (corpora cavernosa) using a small, fine needle. Our pharmacists provide training on proper technique, dosing, and safety.
Are the injections painful?
Most patients feel only mild discomfort or a brief sting at the injection site. Correct technique and rotating injection sides help reduce pain and bruising.
How long do the effects last?
An erection typically develops within 5 to 15 minutes and lasts about 30 to 90 minutes, depending on the dose, formula, and individual response.
What are the possible side effects?
Possible side effects include mild pain at the injection site, bruising, or small nodules. An erection lasting more than 4 hours (priapism) is a medical emergency and needs immediate care.
How should Trimix and Quadmix be stored?
Keep vials refrigerated between 36°F and 46°F (2°C–8°C). Do not freeze. Use an insulated travel container with a cold pack when transporting the medication.
How long does a vial last?
It depends on your prescribed dose and how often you use it. Always follow the beyond-use date on your label, and ask our pharmacists to help estimate when you will need a refill.
Can Trimix and Quadmix be used with oral ED medications?
They should not be combined with PDE5 inhibitors such as sildenafil (Viagra) or tadalafil (Cialis) unless your prescriber approves it, because this can raise the risk of low blood pressure or prolonged erections.
Do I need a prescription?
Yes. Trimix and Quadmix are compounded prescription medications that require a valid prescription from a licensed healthcare provider.
How much do Trimix and Quadmix cost?
Cost depends on the formula, concentration, and vial size prescribed. For current pricing, call 201-444-4190 or email info@rockridgepharmacy.com.
How can my provider send a prescription to Rock Ridge Pharmacy?
Providers can e-scribe to “Rock Ridge Pharmacy,” fax to 201-444-2698, or call 201-444-4190. Patients may also email info@rockridgepharmacy.com for help or refill coordination.
Can I travel with Trimix or Quadmix?
Yes. Keep the medication in an insulated travel cooler with a cold pack and carry it with your prescription label. Avoid leaving it in hot cars or direct sunlight.
How can I contact Rock Ridge Pharmacy for more information?
Call us at 201-444-4190, email info@rockridgepharmacy.com, or visit our Contact Us page.