Compounded Formula • Prescription Required
Sodium Butyrate Suppositories
Rock Ridge Pharmacy compounds Sodium Butyrate Suppositories to support gut health, inflammation management, and anorectal healing, offering a targeted option when standard therapies may not fully resolve symptoms.
Sodium Butyrate Suppositories: Gut & Anal Health Support
Sodium Butyrate is a short-chain fatty acid naturally produced in the gut that plays a key role in maintaining colon health and reducing inflammation.
As a suppository, Sodium Butyrate delivers localized therapeutic effects, supporting tissue repair, reducing pain, and enhancing mucosal healing in the lower gastrointestinal tract.
At Rock Ridge Pharmacy, we prepare Sodium Butyrate suppositories in USP <795> / <800>-compliant facilities, ensuring purity, precision, and customized dosing for each patient.

How Do Sodium Butyrate Suppositories Work?
Anti-Inflammatory Effect
Sodium Butyrate reduces inflammation in the intestinal lining, making it useful for conditions like colitis, Crohn’s disease, and diverticulitis.
Tissue Repair & Healing
It supports mucosal regeneration, helping repair damaged tissues in the colon and anal canal.
Gut Microbiome Support
Butyrate nourishes healthy gut bacteria, contributing to improved digestive balance and reduced IBS symptoms.
Benefits of Sodium Butyrate Suppositories
Reduces Inflammation
Helps calm irritation in the colon and anal canal, providing relief for inflammatory bowel conditions.
Promotes Healing
Supports mucosal repair and tissue regeneration in the lower GI tract.
Localized Effect
Delivers targeted relief with minimal systemic side effects.
How to Use Sodium Butyrate Suppositories
A simple step-by-step guide for safe application and effective results.
Step 1: Preparation
Wash hands thoroughly. If needed, lightly moisten the suppository with water for easier insertion.
Step 2: Insertion
Gently insert the suppository into the rectum, pointed end first, as directed by your prescriber.
Step 3: Aftercare
Remain lying down for a few minutes to allow absorption. Wash hands again after application.
Conditions Treated with Sodium Butyrate Suppositories
Ulcerative Colitis
Helps reduce inflammation and promote healing of the colon lining.
Crohn’s Disease
Aids in managing inflammation and supporting tissue repair.
Diverticulitis
Assists in symptom relief and promotes gut health.
Irritable Bowel Syndrome (IBS)
Supports gut function and may reduce IBS symptoms.
Anal Fissures
Promotes healing of anal canal tears and reduces pain.
Sodium Butyrate Suppositories Dosage
Dosage may vary depending on your provider’s instructions, but most patients follow this standard guidance:
Typical Strength
Commonly compounded at 264mg per suppository.
Frequency
Insert rectally once or twice daily as directed by your prescriber.
Duration
Treatment length varies by condition; follow your provider’s guidance for best results.
Storage & Safety Information
Proper storage ensures the effectiveness of Sodium Butyrate suppositories.
Storage Guidelines
Store refrigerated unless otherwise directed. Keep away from heat, moisture, and direct sunlight. Always follow your pharmacist’s instructions.
Safety & Side Effects
Common: mild local irritation or discomfort.
Rare: gastrointestinal upset or sensitivity.
Use only as prescribed. This is for educational purposes and not a substitute for medical advice.
Cost of Sodium Butyrate Suppository Compounding
Pricing depends on factors like dose strength (commonly 264mg), quantity, and customizations.
For a personalized quote, please call (201) 444-4190 or email info@rockridgepharmacy.com.

Why Choose Rock Ridge Pharmacy for Sodium Butyrate Suppositories?
- Custom compounding with precise 264mg dosing or tailored strengths.
- USP <795> / <800> compliant lab, ensuring purity, accuracy, and safety.
- Fast turnaround — many orders prepared within 24–48 hours and shipped directly to patients.
Our compounding pharmacists collaborate with prescribers to deliver formulations that optimize comfort, gut health, and healing outcomes.
FAQs About Sodium Butyrate Suppositories at Rock Ridge Pharmacy
What are Sodium Butyrate Suppositories?
Sodium Butyrate suppositories are a compounded therapy designed to support gut health, reduce inflammation, and promote healing in the lower gastrointestinal tract and anal canal.
What Conditions Can They Treat?
They are commonly used for ulcerative colitis, Crohn’s disease, diverticulitis, IBS, and anal fissures, where local healing and anti-inflammatory effects are needed.
How Do Sodium Butyrate Suppositories Work?
Butyrate is a short-chain fatty acid that reduces inflammation, supports mucosal repair, and nourishes healthy gut bacteria, promoting overall colon health.
What is the Typical Dosage?
The suppositories are often compounded at a 264mg dose. Your prescriber may tailor the dose based on your condition and therapeutic goals.
How Do I Use Sodium Butyrate Suppositories?
They are inserted rectally, usually once or twice daily as directed. Always follow your prescriber’s instructions for proper use and duration.
Are There Any Side Effects?
Most patients tolerate them well. Mild local irritation or minor digestive changes may occur. Serious side effects are rare. Contact your provider if you experience concerning symptoms.
Do I Need a Prescription?
Yes. Sodium Butyrate suppositories require a valid prescription. Prescribers can send prescriptions directly to Rock Ridge Pharmacy.
Can Rock Ridge Pharmacy Ship These Suppositories?
Yes. We provide statewide shipping across New Jersey for valid prescriptions. Please contact our team for delivery details.
Can I Speak to a Pharmacist?
Absolutely. Our pharmacists are available to discuss dosing, application, side effects, and safe use to ensure the best results from your therapy.
Take Control of Your Digestive Health Today
Call (201) 444-4190 or book online today. Our pharmacists are here to support your unique gastroenterology needs with personalized compounded medications.