Veterinary Ophthalmic Care • Prescription Required
Desmopressin Acetate Eye Drops for Pets
Custom-compounded ophthalmic solutions that support pets with bleeding disorders such as von Willebrand’s disease and mild hemophilia.
Veterinarian-prescribed • Pharmacist-guided • Pet-approved
What Is Desmopressin Acetate?
Desmopressin Acetate is a synthetic analog of vasopressin that improves clotting by boosting von Willebrand factor and Factor VIII levels. In ophthalmic form, it helps pets with bleeding disorders requiring eye care.
Our drops are compounded in a PCAB-accredited facility under USP <797>-compliant, sterile conditions to ensure safety and consistency.
Rock Ridge Pharmacy provides custom strengths and preservative-free options, ensuring care that is veterinarian-prescribed, pharmacist-guided, and pet-approved.

Why Use Compounded Desmopressin Acetate?
Desmopressin acetate is not commercially available in ophthalmic form. Compounding ensures safe, effective, and tailored therapy for pets with bleeding disorders.
Custom Concentrations
Prepared in strengths specific to your pet’s clotting support needs.
Sterile Formulation
Compounded under USP <797> sterile conditions for safety.
Preservative-Free
Available without preservatives to minimize irritation in sensitive eyes.
Alternative Delivery
Eye-drop form provides clotting support when systemic use isn’t preferred.
Pharmacist Expertise
Expert handling of clotting medications for safe veterinary application.
How Desmopressin Acetate Works
Desmopressin acetate enhances clotting factors and supports localized hemostasis, making it valuable for pets with bleeding disorders or eye-related surgical needs.
Stimulates Clotting Factors
Promotes release of von Willebrand factor and increases Factor VIII activity.
Improves Hemostasis
Helps reduce bleeding time in mild to moderate clotting disorders.
Localized Action
Provides clotting support directly in eye tissues where bleeding risk is high.
Supports Eye Surgery
Useful before or after ocular procedures to reduce complications.
Medication | Strength | Form | Base | Primary Use |
---|---|---|---|---|
Desmopressin Acetate | 0.01% | Eye Drops (10ml) | Aqueous | Dry eye, tear stimulation |
Desmopressin Acetate | 0.02% | Eye Drops (10ml) | Aqueous | Moderate dry eye conditions |
Understanding the Base Options
Specialized, preservative-free formulations designed for sensitive eyes in clotting therapy
Sterile Saline
Comfortable, isotonic, and economical — suitable for most clotting applications.
Buffered Saline
pH-adjusted for enhanced comfort and better medication stability over time.
Preservative-Free
Best for frequent use or fragile tissues — prevents irritation and preserves clotting activity.
How to Give the Drops
Step-by-step guide for safe application
Dosage Guidelines & Cost Considerations
Pre-Surgical Use
1 drop in affected eye(s) 30–60 minutes before procedure.
Ongoing Management
Typically 1 drop once or twice daily as prescribed.
Bleeding Episodes
May require dosing every 6–8 hours during active bleeding.
Monthly Cost
Depends on strength & frequency — call Rock Ridge Pharmacy for details.
If You Miss a Dose
Contact your veterinarian, especially if near surgery time.
Treatment Duration
Ranges from single-use (surgery prep) to ongoing management.
Storage & Safety Information
Proper storage and monitoring of Desmopressin Acetate eye drops helps maintain safety and effectiveness.
Storage & Handling
- Keep refrigerated: 36–46°F (2–8°C).
- Protect from light; store in original container.
- Do not freeze or expose to heat.
- Replace cap tightly after each use.
- Keep securely away from children and pets.
Safety & Side Effects
Common mild effects: temporary mild stinging, brief redness, or slight tearing.
Contact your vet if: swelling around the eye, changes in vision, or any signs of excessive clotting appear.
Treatment Timeline & Cost Planning
Pre-Surgical Use
Single application 30–60 minutes before procedure.
Cost: One-time vial use.
Acute Bleeding
Intensive dosing for 1–3 days.
Cost: Higher short-term expense.
Ongoing Management
Regular maintenance dosing as prescribed.
Cost: Consistent monthly cost.
Long-Term
Some pets require extended therapy.
Cost: May lower with reduced dosing.
Veterinary Monitoring
Coagulation tests recommended.
Additional cost: per test panel.

Why Choose Rock Ridge Pharmacy for Veterinary Eye Drops?
- PCAB-accredited & USP <797> sterile lab ensuring safety and quality.
- Veterinary compounding expertise trusted since 1950.
- Custom dosing & formulations for different species and conditions.
- Fast turnaround — most prescriptions ready in 1–2 business days.
- Pharmacist support for storage, use, and follow-up care.
Rock Ridge Pharmacy works with veterinarians and pet owners to provide safe, sterile, and personalized ophthalmic solutions backed by decades of trusted care.
FAQs About Desmopressin Acetate Eye Drops at Rock Ridge Pharmacy
Do I need a prescription?
Yes. Desmopressin acetate is only available with a veterinarian's prescription and requires careful medical supervision due to its effects on blood clotting.
How much will this cost per month?
Monthly costs typically range from $85–155 depending on concentration and dosing frequency. Pre-surgical use may only require a single vial.
Does pet insurance cover this medication?
Many pet insurance plans cover prescription medications for diagnosed bleeding disorders. This is often considered medically necessary treatment.
How quickly does it work?
Effects typically begin within 30–60 minutes of application, with peak effects at 1–2 hours. Duration of action is usually 4–8 hours.
Is this safe for long-term use?
Long-term safety depends on your pet's specific condition and response. Regular veterinary monitoring with coagulation tests is essential.
What if my pet has surgery scheduled?
Coordinate timing carefully with your veterinarian and surgeon. The medication is often applied 30–60 minutes before procedures.
Can this interact with other medications?
Yes, especially other medications affecting blood clotting. Provide your veterinarian with a complete list of all medications and supplements.
Why use eye drops instead of injections?
Topical application provides localized effects with potentially fewer systemic side effects, especially useful for eye-related procedures.
What if I miss a pre-surgical dose?
Contact your veterinarian immediately. The surgery may need to be rescheduled depending on timing and your pet's condition.
How do I know if it's working?
For bleeding control, you should see reduced bleeding. Your veterinarian may perform coagulation tests to measure effectiveness.
Is this the same as human desmopressin?
Similar medication but compounded specifically for veterinary ophthalmic use with appropriate concentrations and sterile preparation.
Can this be used with other eye medications?
Consult your veterinarian about timing and interactions. Some medications may interfere with clotting effects.
What storage precautions should I take?
Keep strictly refrigerated, protect from light, and never freeze. Use a medication refrigerator thermometer to ensure proper temperature.
What if the medication is accidentally left out?
Do not use if left at room temperature for more than 2 hours. Contact us for replacement – effectiveness may be compromised.
Are there side effects I should watch for?
Monitor for signs of excessive clotting, changes in eye pressure, or allergic reactions. Report any concerns immediately.
How is this different from other clotting medications?
Desmopressin works by releasing natural clotting factors rather than providing synthetic ones, often with fewer side effects.
What payment options are available?
We accept cash, credit cards, CareCredit, and can coordinate with pet insurance for direct billing when possible.