Veterinary Ophthalmic Care • Prescription Required
Demecarium Bromide Eye Drops for Pets
Custom-compounded glaucoma therapy and solutions for eyelid muscle disorders in pets.
Veterinarian-prescribed • Pharmacist-guided • Pet-approved
What Is Demecarium Bromide?
Demecarium Bromide is a long-acting cholinesterase inhibitor used to lower intraocular pressure in pets with glaucoma and manage certain eyelid muscle disorders.
Its extended duration of action provides reliable control of serious eye conditions, reducing the need for frequent dosing.
Compounded in a PCAB-accredited, USP <797>-compliant sterile facility, Demecarium Bromide eye drops are prepared with precision to ensure safety, potency, and consistency.

Why Use Compounded Demecarium Bromide?
Demecarium Bromide is not widely available for veterinary use. Compounding ensures precise, safe, and pet-friendly glaucoma treatments.
Custom Concentrations
Typically compounded at 0.125%–0.25% for tailored glaucoma therapy.
Preservative-Free
Available without preservatives to minimize irritation in sensitive eyes.
Flexible Base Options
Formulated in different bases for better comfort and absorption.
Precise Dosing
Ensures accuracy for a potent, long-acting medication like Demecarium.
Pharmacist Expertise
Prepared in sterile, accredited facilities under veterinary guidance.
How Demecarium Bromide Works
Demecarium Bromide lowers eye pressure and supports muscle function, making it highly effective for glaucoma and certain eyelid disorders in pets.
Blocks Cholinesterase
Inhibits cholinesterase enzyme, prolonging neurotransmitter action and reducing intraocular pressure.
Enhances Muscle Function
Improves eyelid muscle contraction in pets with neuromuscular conditions affecting eye movement.
Promotes Fluid Drainage
Increases outflow of aqueous humor, lowering eye pressure and helping protect vision.
Long-Acting Relief
Provides 12–24 hours of effect, supporting consistent glaucoma control with fewer doses.
Medication | Strength | Form | Base | Primary Use |
---|---|---|---|---|
Demecarium Bromide | 0.125% | Eye Drops (5ml) | Aqueous | Glaucoma, muscle disorders |
Demecarium Bromide | 0.25% | Eye Drops (5ml) | Aqueous | Severe glaucoma cases |
Understanding Base Options & Costs
Customized bases influence comfort, absorption, and pricing for glaucoma therapy
Aqueous (Water-Based)
Fast-absorbing, clear solution that does not blur vision. Most economical choice for many glaucoma cases.
Oil-Based
Provides longer tissue contact time, better for pets needing maximum exposure. Higher cost due to complex compounding.
How to Give the Drops
Step-by-step guide for safe application
Dosage Guidelines & Cost Considerations
Typical Dose
1 drop in affected eye(s) once or twice daily as directed.
Glaucoma Management
Often once daily dosing due to 12–24 hour duration of action.
Muscle Disorders
May require twice daily dosing during initial therapy.
Monthly Cost
Varies by strength & frequency — call Rock Ridge Pharmacy for details.
If You Miss a Dose
Give when remembered, but maintain at least 12 hours between doses.
Safety Note
Never exceed prescribed frequency — this medication has cumulative effects.
Storage & Safety Information
Proper handling and monitoring of Demecarium Bromide drops helps maintain safety and effectiveness.
Storage & Handling
- Store refrigerated: 36–46°F (2–8°C).
- Keep in original container, protected from light.
- Do not freeze or expose to heat.
- Replace cap tightly after each use.
- Keep securely away from children and pets.
Safety & Side Effects
Common mild effects: brief eye irritation, redness, or small pupils (miosis).
Contact your vet if: drooling, muscle tremors, breathing difficulty, vomiting, or severe eye pain occurs.
Treatment Timeline & Cost Planning
Initial Response
Pressure reduction usually seen within 2–4 hours.
Cost: Highest during early monitoring phase.
Peak Effect
Maximum effect at 4–6 hours after application.
Cost: Ongoing monitoring and vet follow-up.
Duration
Effects last 12–24 hours per dose.
Cost: May allow less frequent dosing over time.
Long-term Management
Regular vet checks every 2–4 weeks initially.
Cost: Medication + monitoring, call pharmacy for details.
Effectiveness Assessment
Response usually evaluated after 2–4 weeks of consistent use.
Total initial cost: Includes first month of medication + monitoring, call pharmacy.

Why Choose Rock Ridge Pharmacy for Veterinary Eye Drops?
- PCAB-accredited & USP <797> sterile lab ensuring safety and quality.
- Veterinary compounding expertise trusted since 1950.
- Custom dosing & formulations for different species and conditions.
- Fast turnaround — most prescriptions ready in 1–2 business days.
- Pharmacist support for storage, use, and follow-up care.
Rock Ridge Pharmacy works with veterinarians and pet owners to provide safe, sterile, and personalized ophthalmic solutions backed by decades of trusted care.
FAQs About Demecarium Bromide at Rock Ridge Pharmacy
Do I need a prescription?
Yes. Demecarium bromide is only available with a veterinarian's prescription and requires specialized handling and monitoring.
How much will this cost overall?
Monthly medication costs $95–155, plus required veterinary monitoring ($150–300/month initially). Total treatment costs typically $250–450/month during initial phase.
Does pet insurance cover this specialized medication?
Many pet insurance plans cover prescription medications for glaucoma when medically necessary. Keep all receipts including monitoring visits.
How quickly does it work?
Eye pressure reduction typically begins within 2–4 hours, with peak effects at 4–6 hours and duration lasting 12–24 hours per dose.
Why is this more expensive than other glaucoma medications?
This is a highly specialized, potent medication requiring expert compounding, extensive safety measures, and intensive monitoring, which is reflected in the pricing.
Is this safe for long-term use?
When properly monitored by your veterinarian with regular examinations and pressure checks, it can be used long-term for glaucoma management.
What makes this different from other glaucoma drops?
Demecarium bromide is much more potent and longer-acting than most glaucoma medications, but also requires more careful monitoring due to systemic effects.
What if I accidentally give too much?
Contact your veterinarian immediately. Signs of overdose include excessive salivation, muscle weakness, or breathing difficulties. Emergency care may be needed.
Why is regular monitoring so important?
This medication can have systemic effects, and eye pressure needs regular checking to ensure effectiveness while preventing over-treatment.
Can humans accidentally absorb this medication?
Yes – always wash hands thoroughly before and after application. Avoid direct contact. If accidental exposure occurs, seek medical attention.
What if my pet's eye pressure isn't controlled?
Your veterinarian may adjust concentration, frequency, or add additional medications. Our pharmacist will work with your vet to optimize treatment.
How do I know if it's working?
Your veterinarian will measure eye pressure regularly. You may notice your pet seems more comfortable and shows less signs of eye pain.
Can this be used with other glaucoma medications?
Sometimes, but requires careful coordination due to potential interactions. Your veterinarian will manage any combination therapy.
What if the medication accidentally freezes?
Do not use frozen medication. Contact us immediately for replacement as freezing affects this medication's stability and safety.
Are there less expensive alternatives?
While other glaucoma medications exist, demecarium bromide is chosen for specific cases where its unique properties are needed. Discuss options with your veterinarian.
What payment options are available for this expensive treatment?
We accept cash, credit cards, CareCredit, and offer payment plans for long-term treatments. Pet insurance direct billing available when possible.
How do I safely dispose of unused medication?
Never dispose in regular trash or down drains. Return unused medication to our pharmacy for safe disposal due to its potent nature.
What if my pet experiences side effects?
Contact your veterinarian immediately. Our pharmacist is available for emergency consultation regarding potential medication-related issues.