Buprenorphine

Veterinary Compounding Medication – Customized for Dogs and Cats

Quick Reference

Commonly Prescribed For: Pain Management

Species: Dogs and Cats

Therapeutic Class: Opiate

Basic Information

Buprenorphine is a synthetic opiate that acts as a partial agonist at mu-opioid receptors in the brain. It effectively blocks pain perception while producing fewer side effects than full opioid agonists such as morphine. Due to its high receptor affinity, buprenorphine is commonly used to manage mild to moderate pain in dogs and cats, particularly after surgery or injury.

Veterinary Medicine Uses

Pain Management: Buprenorphine is effective for managing pain from tissue inflammation, trauma, and muscle spasms. It is widely used for postoperative and chronic pain control.

Buccal Administration: Especially common in cats, buprenorphine can be absorbed through the oral mucosa (buccal route), offering a less invasive alternative to injections.

Precautions

DEA Regulation: Buprenorphine is a controlled substance under DEA regulations and is typically administered in-clinic by licensed veterinary professionals.

Contraindications: Avoid use in animals with Addison’s disease, severe kidney or liver dysfunction, head trauma, or cardiovascular conditions. Geriatric pets should be monitored closely due to potential respiratory and circulatory sensitivity.

Side Effects

The most common side effect of buprenorphine is sedation. Some animals may also experience mild respiratory depression or gastrointestinal disturbances. These effects are typically short-lived and dose-dependent. Severe reactions are rare when the drug is used as directed by a veterinarian.

Drug Interactions

Buprenorphine may interact with other central nervous system (CNS) depressants such as sedatives, tranquilizers, and anesthetics, potentially enhancing sedative or respiratory effects. Concurrent use with other opiates can alter its analgesic activity due to competitive receptor binding.

Administration Tips

Follow the veterinarian’s prescription for dosage and frequency. Buprenorphine may be administered intravenously, intramuscularly, or via the buccal route depending on the animal’s condition and pain severity.

Handling: As a controlled substance, buprenorphine must be handled according to strict legal and medical protocols to ensure safety and compliance.

Custom Veterinary Compounding for Buprenorphine

For safe and effective veterinary compounding of Buprenorphine and other pain management medications, trust Rock Ridge Pharmacy. Contact our experienced pharmacy team for tailored formulations and professional support for your pet’s needs.