• Common Uses: Inflammation, Immunosuppression, Pruritis, Recurrent airway obstruction in horses
  • Species: Dogs, Cats, and Horses
  • Therapeutic Class: Glucocorticoid

Basic Information:

Prednisolone Acetate is an adrenocortical steroid widely used in veterinary medicine to reduce inflammation. It is commonly administered as eye drops or an injectable solution to manage inflammation and immune responses in dogs, cats, horses, and cattle.

Veterinary Medicine Uses:

  • Anti-inflammatory and Immunosuppressive Effects: Prednisolone Acetate acts by binding to glucocorticoid receptors, modifying protein production, which in turn suppresses inflammation and the immune response.
  • Therapeutic Applications: It is frequently prescribed for pain and inflammation associated with surgeries, injuries, infections, and chronic conditions such as recurrent airway obstruction in horses.

Potential Side Effects:

  • Reproductive Risks: Use in pregnant animals may lead to premature birth or birth defects. Caution is advised when administering to nursing animals.
  • Common Adverse Effects: Watch for signs of adverse reactions such as itching, facial swelling, or respiratory distress.


  • Allergic Reactions: Do not use in animals allergic to ingredients in Prednisolone Acetate. Compounded formulations may be necessary for sensitive animals.
  • Ocular Health: Avoid use in animals with eye ulcers, as the medication can exacerbate this condition.
  • Infection Risk: Long-term use may increase the risk of fungal or bacterial infections.
  • Discontinuation: Gradual tapering is necessary when discontinuing treatment that has been extended over several weeks to avoid severe withdrawal effects.