Amlodipine
Veterinary Compounding Medication – Customized for Dogs and Cats
Quick Reference
Basic Information
Amlodipine is a calcium channel blocker that helps manage hypertension in dogs and cats. It works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle cells, allowing the blood vessels to relax and dilate. This action reduces blood pressure and decreases the heart’s workload.
Amlodipine is well absorbed orally and can be given with or without food. Its effects develop gradually, with maximum efficacy reached several hours after administration.
Uses in Dogs and Cats
Cats: Commonly prescribed for hypertension associated with kidney disease, hyperthyroidism, or heart disease. It helps protect vital organs such as the kidneys, eyes, and brain from high blood pressure damage.
Dogs: Used less frequently but can be effective for treating hypertension secondary to chronic kidney disease or heart failure. Its long duration of action allows for once-daily dosing, maintaining stable blood pressure control throughout the day.
Side Effects
Common side effects include mild lethargy, loss of appetite, vomiting, or in rare cases, gum swelling or increased heart rate. Most reactions are mild and transient.
Serious side effects are uncommon but require immediate veterinary attention. These include extreme weakness, signs of shock, or allergic reactions such as facial swelling or hives.
Precautions
Amlodipine should be used cautiously in pets with severe cardiac or liver disease, as it may affect heart function and is metabolized in the liver. It is not recommended for use in pregnant or lactating animals or those with a history of hypersensitivity to the drug.
Drug Interactions
When combined with other medications that lower blood pressure, amlodipine can increase the risk of excessive hypotension. Additionally, grapefruit juice may interfere with its metabolism, potentially increasing blood levels and side effect risk.
Overdose
Overdose may cause dangerously low blood pressure, severe weakness, or collapse. Immediate veterinary intervention is essential. Supportive care may include intravenous fluids, vasopressor medications to stabilize blood pressure, and cardiac rhythm monitoring.
Custom Veterinary Compounding for Amlodipine
For reliable veterinary compounding of Amlodipine and other animal medications, trust Rock Ridge Pharmacy. Contact our pharmacy team to discuss dosage customization, flavors, and administration options for your pet.
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