SL Semgalutide

What is Sublingual Semaglutide?

It is a compounded suspension of semaglutide designed to be administered under the tongue (sublingually). This innovative formulation leverages Rybelsus® tablet content and a specialized base (SUBMAGNA HMW) meticulously crafted to carry high molecular weight substances like semaglutide through the oral mucosal membrane.

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Daily Dose & Easily Adjustable

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Compliant & No Supply Issues

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No Shots. No Needles. No Fridge.

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Smoother Drug Conc. Curves

How Sublingual Semaglutide is Different?

  • Advanced Formulation Design: Our formulation boasts a unique compounding base with permeation-enhancing and mucoadhesive properties. This design facilitates the efficient transport of Semaglutide molecules into oral tissues, as evidenced by recent in vitro studies demonstrating successful delivery through human gingival and oral tissues.
  • Enhanced Bioavailability: By bypassing the gastrointestinal tract, Sublingual Semaglutide offers improved bioavailability compared to traditional oral medications. This translates to more consistent drug levels in the bloodstream and potentially enhanced therapeutic effects.
  • Rapid Onset of Action: The sublingual route allows for rapid absorption of semaglutide, leading to a quicker onset of therapeutic effects. Patients may experience relief sooner, improving treatment outcomes and overall satisfaction.
  • Minimized Gastrointestinal Side Effects: Sublingual administration may reduce the incidence of gastrointestinal side effects commonly associated with oral semaglutide formulations. Avoiding the digestive system diminishes the likelihood of such adverse reactions.

Benefits of Sublingual Semaglutide:

  • Enhanced Patient Experience: With its sublingual administration and potential for reduced side effects, Sublingual Semaglutide offers patients a more comfortable and tolerable treatment experience.
  • Optimized Treatment Outcomes: The enhanced bioavailability and rapid onset of action of Sublingual Semaglutide contribute to more effective and predictable treatment outcomes.
  • Potential Therapeutic Advancements: As research progresses, Sublingual Semaglutide holds promise for revolutionizing the treatment landscape for conditions requiring Semaglutide therapy.
Bioidentical Hormone Replacement Therapy: Who Can Benefit from Hormonal Balance?

For Healthcare Providers:

  • Flexible Dosing, Optimized Treatment
    • Tailoring Sublingual Semaglutide dosing is straightforward. Adjustments can be made by simply increasing or decreasing the volume administered under the tongue.
    • Considering semaglutide's half-life of approximately 7 days, reaching steady-state concentrations typically takes 4-5 weeks. With daily dosing, patients may experience a smoother titration process and steadier concentration levels. Monitoring patient response and adjusting doses accordingly ensures optimized treatment outcomes.

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    For Patients:

    • Beginning semaglutide treatment? Your healthcare provider may recommend a titration process to ease into it, starting with a smaller dose and gradually increasing. Titrating helps minimize side effects like nausea. Remember, it can take up to 4-5 weeks to reach maximum medication levels after a dose increase.
    • Semaglutide comes in a convenient amber bottle with a 1ml dropper for easy under-the-tongue administration. Store at room temperature, shake before use and apply under your tongue for at least 90 seconds (ideally 5 minutes). Avoid eating or drinking for 30 minutes afterward. Stay in touch with your provider for guidance.

    Ways to Send in Prescriptions

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    1. Fax

    Write a prescription on a prescription pad and fax over to 201-444-2698.

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    2. E-Scribe

    E-Rx (E-scribe) to “Rock Ridge Pharmacy”

    Make sure our address is 191 Rock Rd, Glen Rock, NJ 07452.

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    3. Call

    Call in your prescription to 201-444-4190.

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    4. Fill Out Pre-made Rx Order Forms from Rock Ridge Pharmacy

    Fill out Rock Ridge Pharmacy Rx Order Forms and Fax »

    Access to these Rx Forms is exclusively for physicians. Click here to request access.

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    5. Telemedicine

    Rock Ridge Pharmacy, in partnership with Physician 360, offers on-demand telemedicine consultations for LDN and other conditions. Learn more below.

    How To Start

    START NOW

    Follow the steps below to get started and to sign up for a consultation!

    1. Click Start Now (Green Button Above)
    2. Create account and log-in at visit.physician360.co [start now button above]. Take a brief questionnaire about your symptoms or reason you would like to speak to a provider
    3. Within approximately 5-10 minutes, connect with a medical professional on your phone or your computer [if an RX is warranted, the RX will be sent to Rock Ridge Pharmacy right after the call]
    4. If needed, a prescription will be electronically sent to our team at Rock Ridge Pharmacy.